Maybe invest in a switching pedal that can give you A/B and A+B. And do something like this:I played my Plexi for the first time last night at band rehearsal. Overall, it sounded ok. I'm still trying to get it dialed in to where I have a good overdrive tone with a good amount of cleanup when I roll back the guitar volume. It also seemed like a constant fight between too bassy and not enough bass. But my biggest issue is that leads just seemed to disappear in the mix. I've always boosted the lead volume through an effects loop, but the Plexi obviously doesn't have one. I had both a Boss SD1 with level up, gain down, and an EQ pedal set to frown with level up. I also tried using the guitar volume, but since I already have the amp dialed in with overdrive, raising the guitar volume just seemed to increase gain, not volume. Nothing seemed to really cut my leads up in the mix. Looking for some suggestions.
Or get a Boss LS2 and set the first output lower than unity gain to underdrive the amp. Use this as your rhythm tone and wind back guitar volume for cleans. Then switch to the second output at unity gain for your lead tones and a jump in volume.