Yeah, the big stars don't haul 4x12s up out of their basements by themselves to go play a local bar. I don't mind carrying my combos but one does have to be careful at 50+ how the amps are hauled and managed. Put your back out moving wrong and suddenly you can't gig anymore, at least for awhile.
I like solid, well made stuff but yeah, some of us non weight lifters don't care for hauling heavy pieces up stairs and into the back of an SUV, unload at a show, get it on the stage and do the reverse at 2 AM. Don't get me wrong, it's worth it but lately lighter pieces are becoming more fun for me. Ie - 6101 combo.