Just got a VS V2 Route 808.
With the Marshall:
This pedal lights up the red channel. Not much else to say other than its all good. It sounds good on the crunch channel. Good ole' blues or rock. On the clean you can get some on the edge of break up blues tones.
With the Night Train:
No good here. Dull and flat no matter where the pedals EQ is or the amps. Just average as hell and uninspiring.
The only pedal that sounds good with the NT out of all mine is the CTO-1. It improves the amps tones.
I was going to send the Route 808 back because I got it for the NT specifically. Then I tried it on the DSL and it gave me enough of a variation to the CTO-1 that I decided I could make use of it as another gain flavor and be happy about it.
Almost done(

)with my pedal board. I think the only pedal I still want is the Barber LTD for break up and midgain flavors although the CTO-1 handles all that. The LTD will be a different shade of boost though.